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Please provide a list of the top chemotherapy drugs used in the treatment of breast cancer, including market share of each.
Hi there! Thank you for your request to provide a list of the top chemotherapy drugs used in the treatment of breast cancer, including market share of each. The short version is I have found that there are a number of chemotherapy drugs used in the treatment of breast cancer, including Herceptin ($7.1 billion), Taxotere (US$222 million) , and Xeloda ($1.6 billion). The leading companies include Roche (30.9%, revenue: US$25.7 billion) and Celgene (10.3%, revenue: US$8.6 billion). Below is a deep dive into my research and methodology.
METHODOLOGY
To answer your question, I used Google as my primary research tool. Through Google, I found a number of articles and reports that shed light on the chemotherapy drugs used most often in treating breast cancer. As requested, I have written simple explanations, and I chose an outline format to aid in ease of read.
COMMONLY USED DRUGS IN TREATING BREAST CANCER
- In general, chemotherapy drugs are used in combination as treatment for cancer is unique to the individual.
- The most commonly used drugs for before surgery (neoadjuvant) and after surgery (adjuvant) chemotherapy are:
1) Anthracyclines, (e.g. doxorubicin and epirubicin)
2) Taxanes, (e.g. paclitaxel and docetaxel)
3) 5-fluorouracil
4) Cyclophosphamide
5) Carboplatin
- Advanced breast cancer is more often treated using single chemotherapy drugs rather than combinations. The most commonly used drugs for advanced breast cancer chemotherapy are:
1) Docetaxel
2) Paclitaxel
3) Platinum agents
4) Vinorelbine
5) Capecitabine
6) Liposomal doxorubicin
7) Gemcitabine
8) Mitoxantrone
9) Ixabepilone
10) Albumin-bound paclitaxel
11) Eribulin
TOP COMPANIES IN THE GLOBAL ONCOLOGY MARKET (2015)
- Astellas Pharma Inc. (Japan)
- BioNumerik Pharmaceuticals, Inc. (US)
- Cascadian Therapeutics (US)
- Merck & Co., Inc. (US)
- Novartis AG (Switzerland)
- OncoGenex Pharmaceuticals Inc. (US)
- Pfizer (US)
TOP 6 DRUGS (BY REVENUE) FOR BREAST CANCER
- Company: Roche
- Overview: Avastin is a tumor-starving therapy that prevents the growth of new blood vessels
2. Herceptin (Trastuzumab)
- Company: Roche
- Overview: See below
3. Xeloda (Capecitabine)
- Company: Roche
- Overview: See below
- Company: Novartis
- Overview: Afinitor is a targeted therapy that limits the amount of estrogen so that tumors cannot grow as rapidly.
- Company: AstraZeneca
- Overview: Zoladex is a targeted therapy that limits the amount of estrogen so that tumors cannot grow as rapidly.
6. Ibrance
- Company: Pfizer
- Overview: Ibrance is a targeted hormone therapy that interferes with the growth and spread of cancer cells.
TOP 5 CHEMOTHERAPY DRUGS (BREAST CANCER)
1. Herceptin
- Company: Roche
- Overview: It is used in combination with other drugs to treat HER2-positive breast cancer. HER2 stands for "Human Epidermal growth factor Recepter 2) and it is a protein that encourages the growth of cancer cells.
2. Xeloda
- Company: Roche
- Overview: Xeloda (Capecitabine) attacks specific cells, fusing with them and preventing them from dividing.
- Company: Celgene
- Overview: Abraxane works to prevent cancer cells from dividing.
- Company: Sanofi
- Overview: Taxotere works to prevent cancer cells from dividing.
- Company: Eisai
- Overview: Halaven works to stop cancer cells from dividing by interfering with a component of cells called microtubilin.
CONCLUSION
To wrap it up, the above list represents my findings on some of the top (by revenue) chemotherapy drugs used in the treatment of breast cancer. I have provided you with information on companies that have the highest revenue in the industry as well as included information on other drug therapies that are being used in the treatment of breast cancer. Thanks for using Wonder! Please, let us know if we can help with anything else!