Mesothelioma Market Analysis

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Mesothelioma Market Analysis

Information on the psychographics of mesothelioma patients is severely limited, with most information focusing on the demographics of a typical patient. The typical mesothelioma patient is an older man (65+) with a blue collar or military background. Therefore, the research team used a sample of mesothelioma patient biographies, additional literature on the disease, and information about the general psychographics of older, blue-collar men (the typical demographics of a mesothelioma patient) to craft a psychographic profile of a mesothelioma patient.

Habits

  • Men working in blue-collar jobs tend to have unhealthy habits, like smoking. Those employed in mining, manufacturing, construction, warehousing, and transportation have higher smoking rates than those employed in other occupations.
  • Older blue-collar individuals are at a higher risk of depression.
  • Additionally, blue-collar males had unhealthy habits including poor nutrition, low levels of physical activity, and high levels of alcohol consumption.
  • Many mesothelioma patients report improving their nutrition and other lifestyle factors after their diagnosis as a way to aid in their treatment.

Hobbies

  • Many blue-collar workers are still working after age 65, but have switched to a less physically demanding career, like mentoring or teaching. Some also switch to providing pricing quotes for the industries they were previously employed in.
  • Many older men also enjoy volunteering.
  • Some mesothelioma survivors reported becoming involved in causes related to mesothelioma, such as raising awareness or contributing to research.

Spending

  • Retirees tend to be "thrifty" and "try not to buy frivolous items or spend money lavishly."
  • Many retirees give money to children or other family members that have problems, including divorce or mental illness.
  • The typical blue-collar consumer spends more of their total income on food expenditures than white-collar consumers. They also spend less on housing and medical care.
  • Many mesothelioma patients do some spending related to the disease, including healthcare costs, travel costs, and spending on bucket-list or commemorative activities.

Values

  • Older blue-collar workers value hard work and are "committed to their fields."
  • Blue-collar workers are proud of their work.
  • Blue-collar workers want to help their children and grandchildren financially.
  • Many mesothelioma patients mention their family values and their gratitude for the time they have been given to live.

Mesothelioma Trends

Age

  • Currently, people aged "80-84 have the highest mesothelioma incidence with 8.9 new cases per 100,000."
  • Women are typically diagnosed younger than men, which could explain why they tend to live longer.
  • In general, younger patients diagnosed with mesothelioma live longer post-diagnosis.
  • 57.2% of patients younger than 50 will survive for at least one year post-diagnosis, while the same can be said for 51.2% of patients 50 – 64, 40.9% of patients 65 – 74, and only 28.5% of patients older than 75.

Gender

  • 80% of mesothelioma patients are men. However, the incidence rate for women is increasing, and is edging closer to 25%.
  • The typical latency period for mesothelioma in women is 53.3 years and 47.9 years for men.
  • Women diagnosed with mesothelioma typically live longer than men diagnosed with the disease.
  • 45.4% of women diagnosed with mesothelioma live at least one year after diagnosis, compared to only 37.6% of men. Two years after diagnosis, 29.3% of women survive compared to 17.4% of men. 22.2% of women survive three or more years, while only 10.4% of men do. Four years after diagnosis, 18.6% of women survive compared to 7.7% of men. Finally, 16.0% of women survive five years after diagnosis, while only 5.9% of men do.

Geographic Incidence

  • States with the highest incidence rate of mesothelioma are Alaska, New Jersey, Washington, Maine and West Virginia.
  • California has the highest death rates from mesothelioma, due to the high rate of naturally occurring asbestos. Florida has the second highest death rate, and New York is believed to have the potential for a high death rate due to the release of asbestos from the 911 Twin Towers terrorist attack.
  • The incidence rates are higher in areas that also had high rates of exposure to asbestos, like those with a history of shipbuilding and industry.
  • The overall incidence rate for the US is 1.51 per 100,000 people.
  • Hot spots in the US for mesothelioma are Manville, New Jersey (due to the Johns Manville Corporation asbestos manufacturing plant that operated there from 1912 to 1980), Libby, Montana, Dunn County, North Dakota, El Dorado Hills, California, Clark County, Nevada, and Allegheny County, Pennsylvania (all due to asbestos mines in these areas).
  • Globally, the UK and Australia have high rates of incidence and death from mesothelioma, as do developing countries like China, Kazakhstan, Russia, India, Pakistan, Mexico, Indonesia and Thailand.

Type

  • Pleural mesothelioma is the most common type with an incidence rate of 3.05 cases per 100,000 people. Peritoneal mesothelioma is the second most-common type, with an age-adjusted incidence of only 0.21 cases.
  • 70% of all mesothelioma cases "occur in the pleura, the tissue lining surrounding the lungs". 20% of cases appear in the peritoneum (the lining of the abdomen), while 1% form in the pericardium (the lining of the heart) and less than 1% form in the tunica vaginalis (the lining of the testes).
  • The average latency period for pleural mesothelioma is 30 to 60 years, while the latency period for peritoneal mesothelioma is 20 to 40 years.
  • By stage, those diagnosed with mesothelioma at an earlier stage have a longer survival time. For those diagnosed at stage 1, the survival time is 22.2 months, while for those diagnosed at stage 5, the survival time is only 14.9 months.
  • Patients with peritoneal mesothelioma have longer survival times than those with other forms of mesothelioma, due to the advances in treatment that have been made for peritoneal mesothelioma.

Treatment

  • Most patients, or 80%, receive chemotherapy as a treatment for mesothelioma. Chemotherapy triples the survival rate for patients with pleural or peritoneal mesothelioma.
  • Some patients (less than 20%) are able to get surgery to remove the tumor, and of those that do, half live longer than five years.
  • The most effective treatment for mesothelioma is multimodal therapy, including surgery, chemotherapy and radiation.
  • Some doctors are experimenting with immunotherapy drugs for mesothelioma treatment including Pembrolizumab (Keytruda), Nivolumab (Opdivo), Ipilimumab (Yervoy), CRS-207 and the WT1 Vaccine.
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