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Part
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BRCA Genetic Testing
Our research team identified GeneDx, Ambry, Invitae, Color Genomics, Quest Diagnostics, Bio-Reference Labs, and Gene By Gene as companies headquartered in the United States offering BRCA genetic testing targeting health care providers and health care institutions.
METHODOLOGY
To identify seven firms that offer BRCA genetic testing in the United States, we conducted a press search for genetic companies similar to Myriad Genetics. According to STAT news, a media company focused on "telling compelling stories about health, medicine, and scientific discovery," Myriad was the pioneer of these tests and held a monopoly in the BRCA testing market until 2013, "when the US Supreme Court invalidated the company’s key patents." Right away, competitors began emerging and offering the tests for a lesser price than Myriad. Some competitors mentioned here include GeneDx, Ambry, Invitae, and Color Genomics. Additionally, Investor's Business Daily states that Quest Diagnostics and Bio-Reference Labs are other competitors to Myriad in the breast-cancer (BRCA) gene test market.
Next, we checked their official websites to determine the constituents they target with their marketing. However, since most of the companies in this market do not focus on disclosing their end market, our team had to be creative. If the tests are only available or can be done in a clinical setting or laboratory, we concluded that a firm offers its test products to physicians or large health care institutions. Additionally, the first direct-to-consumer test for BRCA was just recently (2018) approved by the Federal Drug Authority (FDA), and because the companies identified above had been in operation prior, we arrogate that their BRCA genetic tests target physicians or large health care institutions.
GeneDx
GeneDx BRCA genetic test checks for two disorders: the BRCA1/BRCA2 breast cancer gene mutations and ovarian cancer.
The product is available for physicians or health care providers.
Ambry
Ambry BRCA genetic test checks for hereditary breast and ovarian cancer produced by germline BRCA1/BRCA2 mutations.
The product is available for physicians or health care providers.
Invitae
Invitae BRCA genetic test checks for hereditary breast and ovarian cancer syndrome arising from BRCA1 and BRCA2 mutations.
The product is directly marketed to healthcare providers.
Color Genomics
Color’s Hereditary Cancer Test is used to check for hereditary and familial cancer & sporadic cancer caused by BRCA1 mutation and APC mutation respectively.
The product is directly marketed to healthcare providers.
Quest Diagnostics
Quest Diagnostics' BRCAvantage Test "menu, include BRCA1 and BRCA2, and expanded testing for significant breast cancer susceptibility genes."
This BRCAvantage Test is directly marketed to physicians and hospitals.
Bio-Reference Labs
Bio-Reference Labs BRCA genetic test checks for hereditary breast cancer caused by BRCA1 and BRCA2 genes.
The company markets to physicians, correctional health facilities, federally qualified health centers, and hospitals.
Gene By Gene
Gene By Gene Testing is for the detection of BRCA1/2 mutations in breast and ovarian cancer.
Gene By Gene directly markets to health professionals.
Finally, other companies that offer BRCA test targeting only patients are the Mayo Clinic and Foundation Medicine.
Note: All the companies are headquartered in the United States.